Image source: Getty Images. See all posts by Peter Stephens Our 6 ‘Best Buys Now’ Shares Peter Stephens | Sunday, 7th February, 2021 FREE REPORT: Why this £5 stock could be set to surge I would like to receive emails from you about product information and offers from The Fool and its business partners. Each of these emails will provide a link to unsubscribe from future emails. More information about how The Fool collects, stores, and handles personal data is available in its Privacy Statement. Simply click below to discover how you can take advantage of this. Enter Your Email Address A plan to invest £20k, or any other amount, in a Stocks and Shares ISA could be a profitable strategy over the long run. After all, many UK shares currently trade at relatively low prices that may undervalue their prospects.Furthermore, the stock market has a long track record of recovering from even its very worst downturns. And an ISA is exempt from tax. That means its returns could be relatively high when compared to a standard share-dealing account.5G is here – and shares of this ‘sleeping giant’ could be a great way for you to potentially profit!According to one leading industry firm, the 5G boom could create a global industry worth US$12.3 TRILLION out of thin air…And if you click here we’ll show you something that could be key to unlocking 5G’s full potential…Buying cheap stocks in a Stocks and Shares ISAFollowing the 2020 stock market crash, it is still possible to buy UK shares at cheap prices. This may have a positive impact on an investment in a Stocks and Shares ISA over the long run, since purchasing an asset for less than it is worth can lead to attractive returns.Clearly, not every cheap share offers a mix of financial strength and long-term growth potential. Therefore, it is important to check every company thoroughly before purchasing it. However, with many sectors such as banking, energy and retail containing large companies with dominant market positions that trade at low prices, there seem to be numerous opportunities to buy undervalued shares.Stock market recoveryA stock market recovery is never guaranteed to lift the valuation of any Stocks and Shares ISA. After all, a recovery may never occur, or it could fail to positively impact on the valuations of specific stocks that are held in an ISA.However, the past performance of indexes such as the FTSE 100 shows that it has always returned to previous record highs following its declines. Therefore, owning a diverse range of companies in an ISA could lead to high capital returns.Tax efficiency of an ISACompared to a regular share-dealing account, a Stocks and Shares ISA offers significant tax advantages. For example, there is no dividend tax or capital gains tax charged on investments made through an ISA. This could lead to significant tax savings over the long run that produces a larger nest egg.An ISA is also just as easy to open as a standard share-dealing account. It can be done online in a matter of minutes. It offers flexibility in terms of withdrawals being tax and penalty-free. Its cost is likely to be higher than that of an ordinary share-dealing account, but this charge could be more than fully offset by the potential tax savings.Risk reduction in a Stocks and Shares ISAOf course, buying and holding UK shares a Stocks and Shares ISA is, by its very nature, a relatively risky investment. However, through building a diverse portfolio of high-quality companies when they trade at low prices, it is possible to capitalise on a likely long-term stock market recovery. This could lead to a surprisingly large ISA portfolio over the coming years. 3 reasons why I’d invest £20k in a Stocks and Shares ISA today Get the full details on this £5 stock now – while your report is free. Are you on the lookout for UK growth stocks?If so, get this FREE no-strings report now.While it’s available: you’ll discover what we think is a top growth stock for the decade ahead.And the performance of this company really is stunning.In 2019, it returned £150million to shareholders through buybacks and dividends.We believe its financial position is about as solid as anything we’ve seen.Since 2016, annual revenues increased 31%In March 2020, one of its senior directors LOADED UP on 25,000 shares – a position worth £90,259Operating cash flow is up 47%. (Even its operating margins are rising every year!)Quite simply, we believe it’s a fantastic Foolish growth pick.What’s more, it deserves your attention today.So please don’t wait another moment. 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